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Titel Royal jelly ameliorates diet-induced obesity and glucose intolerance by promoting brown adipose tissue thermogenesis in mice

Weiterlesen: Takeshi Yoneshiroa, Ryuji Kaedea, Kazuki...

Titel New propolis type from northeast Brazil: chemical composition, antioxidant activity and botanical origin

Weiterlesen: Joselena M. Ferreira, Caroline C....

Titel Effect of the Egyptian propolis on the hepatic antioxidant defense and pro-apoptotic p53 and anti-apoptotic bcl2 expressions in aflatoxin B1 treated male mice

Weiterlesen: Abeer A. Alm-Eldeen, Mohammed A. Basyony,...

Titel Neurobehavioral and Antioxidant Effects of Ethanolic Extract of Yellow Propolis
Subtitel
Author Cinthia Cristina Sousa de Menezes da Silveira, Luanna Melo Pereira Fernandes, Mallone Lopes Silva, et al., 
Abstract Propolis is a resin produced by bees from raw material collected from plants, salivary secretions, and beeswax. New therapeutic properties for the Central Nervous System have emerged. We explored the neurobehavioral and antioxidant effects of an ethanolic extract of yellow propolis (EEYP) rich in triterpenoids, primarily lupeol and β-amyrin. Male Wistar rats, 3 months old, were intraperitoneally treated with Tween 5% (control), EEYP (1, 3, 10, and 30 mg/kg), or diazepam, fluoxetine, and caffeine (positive controls) 30 min before the assays. Animals were submitted to open field, elevated plus maze, forced swimming, and inhibitory avoidance tests. After behavioral tasks, blood samples were collected through intracardiac pathway, to evaluate the oxidative balance. The results obtained in the open field and in the elevated plus maze assay showed spontaneous locomotion preserved and anxiolytic-like activity. In the forced swimming test, EEYP demonstrated antidepressant-like activity. In the inhibitory avoidance test, EEYP showed mnemonic activity at 30 mg/kg. In the evaluation of oxidative biochemistry, the extract reduced the production of nitric oxide and malondialdehyde without changing level of total antioxidant, catalase, and superoxide dismutase, induced by behavioral stress. Our results highlight that EEYP emerges as a promising anxiolytic, antidepressant, mnemonic, and antioxidant natural product.
Methods
Results
Conclusions
dx.doi.org / URL dx.doi.org/10.1155/2016/2906953
Published  Oxidative Medicine and Cellular Longevity Volume 2016 (2016), Article ID 2906953, 14 pages
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Download this file (2906953.pdf)2906953.pdf 1970 kB2417

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